In this age of health and beauty, every little discovery can make a big difference. We are going to introduce to you A substance that comes from nature and has unlimited potential – urolixin A.

Sources of urolithin A

Urolithin A is A natural product that can be obtained by hydrolyzing tannins in plants such as strawberries and pomegranates. Urolixin A is mainly derived from foods rich in polyphenols, such as pomegranates and other berries, and is metabolized by microorganisms in the human gut. These polyphenol compounds are broken down by specific bacteria in the gut to produce secondary metabolites, including urolithin A, which provide us with multiple health benefits.

The characteristics of urolithin A

(1) High purity: Urolixin A preparations can be obtained through natural extraction and fine manufacturing processes to obtain high purity products. High purity means better bioavailability and fewer adverse reactions.
(2) Safety: Urolixin A is a natural product that has been proven to be safe for humans. There were no toxic side effects in the dose range.
(3) Stability: urolixin A preparation has good stability and can maintain its activity and effect under different environmental and storage conditions.
(4) Easy absorption: urolixin A preparation can be rapidly absorbed by the human body, enter the blood circulation through the intestine, and distribute to different tissues and organs.

Chemical structure of urolithin A

Urolixin A has the chemical formula C13H8O4, CAS number 1143-70-0, and molecular weight 228.2. Its structure contains 3, 8-dihydroxy-6h-dibenzo [B,D] pyrano-6-one ‌. Urolitin A is a kind of diterpenoid compound, its molecular structure contains many ring structures and functional groups. According to different research methods, the structure of urolithin A may be different, but its basic structure is similar. The main source of urolithin A is uric acid in human urine, which is produced through a series of biotransformation processes.

Biological function of urolithin A

1. Antioxidant effect: Urolixin A has a strong antioxidant capacity, which can clear free radicals in the body and reduce oxidative damage. It was found that urolixin A can bind to peroxisome proliferator-activated receptor γ (PPARγ) to activate the PPARγ signaling pathway, thereby enhancing the antioxidant capacity of cells.
2. Anti-inflammatory effect: urolixin A can inhibit inflammatory response and reduce inflammatory damage. It has been found that urolixin A can inhibit the activity of nuclear factor κB (NF-κB) and reduce the production of inflammatory factors, thereby reducing inflammatory damage.
3. Anti-tumor effect: Urolixin A has anti-tumor effect, which can inhibit the growth and spread of tumor cells. It was found that urolixin A can induce apoptosis of tumor cells and inhibit the invasion and metastasis of tumor cells.
4. Protect the cardiovascular system: Urolixin A can protect the cardiovascular system and prevent cardiovascular diseases. Studies have found that urolithin A can reduce blood lipid levels and inhibit the occurrence of atherosclerosis.
5. Anti-aging: urolithin A has the effect of anti-aging, can extend life. It was found that urolixin A could inhibit the activity of telomerase and delay cell senescence. At the same time, urolixin A can also promote the function of mitochondria, improve the level of energy metabolism of cells, and thus delay aging.

Application of urolithin A

1.‌ dietary supplement ‌ : as an inducer of mitochondrial autophagy, urolixin A has the effects of preventing muscle aging, anti-inflammatory, anti-proliferation, restoring mitochondria, improving muscle health and anti-aging ‌.
2.‌ cosmetics ‌ : Urolixin A is also used in skin care products due to its antioxidant and anti-inflammatory properties.
3.‌ medicine and health care products ‌ : urolixin A is also widely used in medicine and health care products, with anti-inflammatory, antioxidant, anti-cancer and other health functions ‌.

Urolixin A, this natural wonder, with its multiple effects and wide application prospects, is becoming an important partner in our pursuit of health and beauty. Let’s look forward to more surprises and changes in the future!